GLP, S-5
Price range: $108.00 through $899.91
S-5 is a synthetic glucagon-like peptide-1 (GLP-1) receptor agonist with molecular formula C187H291N45O59 and molecular weight of 4114 g/mol. This 31-amino acid peptide demonstrates 94% homology with human GLP-1 and contains two amino acid substitutions (Aib8, Arg34) with acylation at Lys26. S-5 is classified as an incretin mimetic and is utilized in research investigating GLP-1 receptor pharmacology and glucose homeostasis mechanisms.
Description
S-5 represents a sophisticated synthetic analogue of glucagon-like peptide-1, engineered to provide enhanced stability and extended duration of action for research applications. The compound exhibits the molecular formula C187H291N45O59 with a molecular weight of 4114 g/mol and demonstrates 94% sequence homology with endogenous human GLP-1. The structural modifications include strategic amino acid substitutions at positions 8 and 34, where Œ±-aminoisobutyric acid (Aib) replaces alanine at position 8 and arginine substitutes for lysine at position 34. Additionally, the peptide features acylation at lysine-26 with a C18 fatty acid chain, which significantly extends the compound’s half-life through albumin binding. Semaglutide functions as a selective GLP-1 receptor agonist, demonstrating high binding affinity and activation of GLP-1 receptors in laboratory systems.
For research use only.
| Quantity | 1bottle, 3bottles, 5bottles, 10bottles |
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